Synthesis of Aldehydes by Organocatalytic Formylation Reactions of Boronic Acids with Glyoxylic Acid
نویسندگان
چکیده
منابع مشابه
Organocatalytic, enantioselective synthesis of benzoxaboroles via Wittig/oxa-Michael reaction Cascade of α-formyl boronic acids.
An unprecedented enantioselective synthesis of 3-substituted benzoxaboroles has been developed. An in situ generated ortho-boronic acid containing chalcone provides the chiral benzoxaboroles via an asymmetric oxa-Michael addition of hydroxyl group attached to the boronic acid triggered by the cinchona alkaloid based chiral amino-squaramide catalysts. In general, good yields with good to excelle...
متن کاملOxidation and reduction of glycolic and glyoxylic acids in plants. II. Glyoxylic acid reductase.
Clagett, Tolbert, and Burris (1) discovered an enzyme of wide-spread occurrence in the green parts of many plants which catalyzes the oxidation of glycolic and L-lactic acids. The enzyme, which was partially purified from tobacco leaves, seemed to catalyze the oxidation of glycolic acid, through glyoxylic acid, to formic acid and CO, (2). In view of the possible importance of glycolic acid oxid...
متن کاملnano-rods zno as an efficient catalyst for the synthesis of chromene phosphonates, direct amidation and formylation of amines
چکیده ندارد.
syn-Selective asymmetric cross-aldol reactions between aldehydes and glyoxylic acid derivatives catalyzed by an axially chiral amino sulfonamide.
syn-Selective asymmetric cross-aldol reactions of aldehydes with tert-butyl glyoxylate and glyoxamide were realized by the use of an axially chiral amino sulfonamide (S)-1. The cross-aldol products obtained are densely functionalized and readily converted to synthetically useful and important chiral building blocks such as γ-lactone and γ-lactam.
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ژورنال
عنوان ژورنال: Angewandte Chemie
سال: 2017
ISSN: 0044-8249,1521-3757
DOI: 10.1002/ange.201703127